Friday, 10 February 2012

Sleepy? No problem!!

Is any one dreamed of becoming a doctor, most of our reply will be yes, such a lucrative job who will say No. But  like there is an unseen side of the moon,there is a hidden other side of such a tantalizing job.Hectic ward duties,sleepless night duty continued with day duty,round the clock duties where sleep deprivation will be most common and a macabre.

A Pleasant Windfall reached at a high time for those who worried concerning the above. 

Yap,other than coffee, a doctor can have a most trust worthy drug to make him sharp even after a day sleep deprivation.

A Drug can make a day sleep deprived fresh.


Study:
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To investigate the effect of modafinil 200 mg on the performance of healthy male doctors after 1 night of supervised sleep deprivation.


Study type:
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parallel, double-blind, randomized, and placebo-controlled study among 39 healthy male resident doctors.


Method-:
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CANTAB neuropsychological tests was used to assess higher cognitive function. 
Clinical psychomotor performance was assessed using the Minimally Invasive Surgical Trainer Virtual Reality.


Findings:
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Fatigued doctors might benefit from pharmacological enhancement in situations that require efficient information processing, flexible thinking, and decision making under time pressure


Explanation:
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Psycho stimulant (like dextroamphetamine and sibutramine)
Exact mechanism not known; modafinil may act via stimulation of hypocretin-containing neurons in the hypothalamus or through inhibition of dopamine reuptake


The Drug is well tolerated;but around 5% cases reported  headache, nausea, nervousness, anxiety, and insomnia


Study publisher- PubMed [link]







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