Dew 4:a single pill!

A new pill to treat HIV infection that combines four medicines and only has to be taken once a day was approved by the U.S. Food and Drug Administration.

Stribild
which will be marketed by maker Gilead Sciences, contains the HIV drugs elvitegravir, cobicistat, emtricitabine and tenofovir disoproxil fumarate. It will be prescribed to people who have never been treated for HIV infection, the agency said in a statement. Two of the drugs, elvitegravir and cobicistat, are new, the FDA noted. Elvitegravir interferes with one of the enzymes that HIV needs to multiply, while cobicistat inhibits an enzyme that metabolizes certain HIV drugs and so prolongs the effect of elvitegravir.

The combination of emtricitabine and tenofovir disoproxil fumarate is already marketed as Truvada, and they work in concert to block another enzyme that HIV needs to replicate.

dew 5: h2o2 potential!

Q:Is it safe to use hydrogen peroxidein cleaning dirty wounds?

A:Yes, but it is not advisable now a days because Peroxide is a solution made up of hydrogen and oxygen. It is a strong oxidizer and can be used as a cleaning agent and to prevent infections. When used topically, this antiseptic foams due to the enzyme catalase. As the catalase comes in contact with the skin it turns the hydrogen peroxide into water and oxygen gas.

 

 According to health experts at the Swedish Medical Center in Colorado, hydrogen peroxide contains too much oxygen for the blood leading to potential issues.  When your skin absorbs hydrogen peroxide, it can reduce the amount of fibroblasts, a particular cell that is imperative for cleaning and repairing damaged tissue

 

 http://www.medicaldaily.com/articles/11831/20120830/the-dangers-of-peroxide.htm#zr2duG06mcuqzeiV.99

Peutz—Jeghers syndrome

Dew3:

There is a congenital condition which presents with acute onset of abdominal pain, vomiting, and abdominal distention in adolescents.

Peutz–Jeghers syndrome, an autosomal dominant disorder characterized by the development of multiple hamartomatous gastrointestinal polyps, mucocutaneous pigmented lesions on the lips or buccal mucosa, and an increased risk of cancer within and outside the gastrointestinal tract.

Dew 2

Single-dose drug cure for malaria

Scientists claim to have discovered a drug that could cure all strains of malaria with a single oral dose and also block transmission of the deadly parasite from person to person. The compound from the aminopyridine class (code named MMV390048) shows potent activity against multiple points in the malaria parasite’s lifecycle. The drug is the first compound researched on African soil to enter preclinical development in partnership with Medicines for malaria venture (MMV), a not-for-profit public-private partnership, in Switzerland. The synthetic molecule from the aminopyridine class, which has been described as novel and potent, not only has the potential to become a single-dose cure for malaria, but researchers are convinced that it could block transmission of the malaria parasite from person to person. The aminopyridine series was initially identified by Griffith University scientists in Australia as part of MMV’s extensive malaria screening campaign of around 6 million compounds. A team of scientists from the University of Cape Town’s (UCT) Drug Discovery and Development Centre (H3-D) in South Africa, led by Professor Kelly Chibale then scrutinised and explored the anti-malarial potential of the series further. With parasitological and pharmacological support from the Swiss Tropical and Public Health Institute and Monash University, respectively, Kelly’s team selected the most promising compounds from the series to be optimized and re-tested. In just 18 months the team had identified and developed a candidate suitable for preclinical development. “We are very excited that this promising compound, researched by African scientists, has been selected by MMV for further development,” Chibale, Founder and Director, UCT H3-D, said. “This is truly a proud day for African science and African scientists! Our team is hopeful that the compound will emerge from rigorous testing as an extremely effective medicine for malaria — a disease that accounts for 24 per cent of total child deaths in sub-Saharan Africa,” Chibale said.

Courtesy : the hindu.

Dew 1

Q:What is the feature shown here?

A:black eyes or racoon's eyes or pandas sign. One of the features of basal skull fracture. Other signs include CSF rhinnorhea.